SCHEMBL25815970

SCHEMBL25815970

Cc1cccc(C)c1-c1nc(C)c(F)c(CO[Si](C)(C)C(C)(C)C)n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25815974 0.75 KDM4E (0.33)
SCHEMBL25815977 0.74
SCHEMBL25815755 0.72
SCHEMBL5467148 0.66 BACE1 (0.39)
SCHEMBL12228067 0.66 CD44 (0.37)
SCHEMBL25263862 0.65 MBOAT4 (0.38) TACR1
SCHEMBL25607621 0.65 TACR1 (0.31) TACR1
SCHEMBL14665867 0.65 NOS3 (0.36)
SCHEMBL3081717 0.64 KDM5A (0.37)
SCHEMBL31254281 0.64 RXRA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125182-A1 PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF 海思科医药集团股份有限公司 2023-07-06 WO disclosed