SCHEMBL25815974

SCHEMBL25815974

Cc1cccc(C)c1-c1nc(C)c(F)c(CO)n1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
F10 P00742 1/20 0.32
HTR7 P34969 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CRHR1 P34998 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25815754 0.76 MAP4K1 (0.36) KDM4EALDH1A1MEN1KMT2A
SCHEMBL25815970 0.75 TACR1 (0.32)
SCHEMBL15464515 0.69 TRPV3 (0.39) HTR7
SCHEMBL18938791 0.65 CYP2A6 (0.43) ALDH1A1
SCHEMBL25815975 0.65
SCHEMBL17532977 0.65 NOS3 (0.42) KDM4E
SCHEMBL20110472 0.64 L3MBTL1 (0.50) ALDH1A1HTR7
SCHEMBL24028061 0.64 NPC1 (0.34) KDM4EALDH1A1CRHR1
SCHEMBL64297 0.64 CRHR1 (0.52) CRHR1
SCHEMBL30212751 0.64 NPC1 (0.34) KDM4EALDH1A1CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125182-A1 PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF 海思科医药集团股份有限公司 2023-07-06 WO disclosed