Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.37 |
| ▸ | CAMK1D | Q8IU85 | 10/20 | 0.35 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.33 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.33 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294415 | 0.88 | RBP4 (0.38) | BTKCAMK1DRBP4RIPK1KDM4E | |
| SCHEMBL25294414 | 0.88 | RBP4 (0.38) | BTKCAMK1DRBP4RIPK1KDM4E | |
| SCHEMBL30338833 | 0.82 | RIPK1 (0.40) | BTKCAMK1DRIPK1KDM4E | |
| SCHEMBL25301445 | 0.82 | RIPK1 (0.40) | BTKCAMK1DRIPK1KDM4E | |
| SCHEMBL25816606 | 0.82 | KDM4E (0.49) | KDM4EPTPN11 | |
| Trifluoroacetic Acid SCHEMBL30338793 | 0.76 | KDM4E (0.43) | RBP4KDM4EPTPN11CYP2C19 | |
| SCHEMBL25817371 | 0.75 | RIPK1 (0.36) | BTKCAMK1DRBP4RIPK1KDM4E | |
| SCHEMBL25817374 | 0.75 | RIPK1 (0.36) | BTKCAMK1DRBP4RIPK1KDM4E | |
| SCHEMBL25253979 | 0.73 | KDM4E (0.55) | KDM4EPTPN11CYP2C19 | |
| SCHEMBL30547531 | 0.73 | KDM4E (0.55) | KDM4EPTPN11CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | SANOFI (FR) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | RIPK1, RIPK4, RIPK2 | BTK 1833/4885CAMK1D 51/4885RBP4 2318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.