Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 9/20 | 0.38 |
| ▸ | MDM4 | O15151 | 5/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25817666 | 0.87 | HIF1A (0.43) | HIF1AMDM2MDM4LMNA | |
| SCHEMBL24894413 | 0.76 | TAS2R14 (0.39) | HIF1ALMNA | |
| SCHEMBL14393899 | 0.74 | CYP2C19 (0.39) | HIF1A | |
| SCHEMBL12376684 | 0.72 | MMP3 (0.39) | HIF1ALMNA | |
| SCHEMBL12410297 | 0.66 | MMP3 (0.40) | LMNA | |
| SCHEMBL12967167 | 0.65 | KMT2A (0.39) | LMNA | |
| SCHEMBL20245188 | 0.63 | MTNR1A (0.39) | — | |
| SCHEMBL24459288 | 0.63 | ACACB (0.39) | — | |
| SCHEMBL13136108 | 0.63 | ACACB (0.39) | — | |
| SCHEMBL24894270 | 0.62 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220028-A1 | MODULATING ANGIOGENESIS BY PROTEOMIMETICS OF VASCULAR ENDOTHELIAL GROWTH FACTOR | UNIVERSITY OF SOUTH FLORIDA | 2023-07-13 | — | — | US | disclosed |
| US-20230220028-A1 | MODULATING ANGIOGENESIS BY PROTEOMIMETICS OF VASCULAR ENDOTHELIAL GROWTH FACTOR | UNIVERSITY OF SOUTH FLORIDA | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230220028-A1 | MODULATING ANGIOGENESIS BY PROTEOMIMETICS OF VASCULAR ENDOTHELIAL GROWTH FACTOR | VEGFA, FLT4, FLT1 | HIF1A 18/4885MDM2 282/4885MDM4 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.