SCHEMBL2581786

SCHEMBL2581786

C[SiH](C)c1cccc(Oc2cccc([SiH](C)C)c2[SiH](C)C)c1[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9787307 0.94
SCHEMBL3837700 0.80
SCHEMBL188298 0.78 CA1 (0.39)
SCHEMBL10339949 0.76 LMNA (0.45)
SCHEMBL5613847 0.70
SCHEMBL7038556 0.70 CYP3A4 (0.40)
SCHEMBL6433975 0.67 CA1 (0.57)
SCHEMBL30937816 0.67 SMN1; SMN2 (0.47)
SCHEMBL8385590 0.67 SMN1; SMN2 (0.47)
SCHEMBL21722359 0.65 PDCD1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048977-B2 Organosilicon polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US claimed
US-20090069525-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY 2009-03-12 US claimed
WO-2007130014-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-15 WO claimed
US-4912242-A Process for preparing silicon esters DOW CORNING CORPORATION (US) 1990-03-27 US claimed
US-20230331928-A1 HYPERBRANCHED POLYMER, METHOD OF MAKING, AND CURABLE COMPOSITION INCLUDING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2023-10-19 US disclosed
US-8084515-B2 Dental compositions containing carbosilane polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-12-27 US disclosed
US-8048977-B2 Organosilicon polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US disclosed
EP-1781724-B1 DENTAL COMPOSITIONS CONTAINING CARBOSILANE POLYMERS 3M INNOVATIVE PROPERTIES CO (US) 2009-07-08 EP disclosed
US-20090069525-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY 2009-03-12 US disclosed
US-20080045626-A1 Dental Compositions Containing Carbosilane Polymers 3M INNOVATIVE PROPERTIES COMPANY 2008-02-21 US disclosed
WO-2007130014-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-15 WO disclosed
EP-1781724-A1 DENTAL COMPOSITIONS CONATAINING CARBOSILANE POLYMERS 3M Innovative Properties Company (US) 2007-05-09 EP disclosed
WO-2006019796-A1 DENTAL COMPOSITIONS CONATAINING CARBOSILANE POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-02-23 WO disclosed
US-20020103328-A1 Aromatic polycarbonate composition, production process therefor and molded product thereof TEIJIN LIMITED 2002-08-01 US disclosed
US-5447988-A Composition for attaching semiconductor device to substrate: polycyanate ester monomer vehicle, electrically conductive filler, metal catalyst. Monomer vehicle is liquid under ambient conditions and composition is alkylphenol-free. QUANTUM MATERIALS (US) 1995-09-05 US disclosed
US-4912242-A Process for preparing silicon esters DOW CORNING CORPORATION (US) 1990-03-27 US disclosed