Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28437143 | 0.96 | PDK2 (0.42) | THRBTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL30501022 | 0.90 | THRB (0.41) | THRBTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL697580 | 0.90 | MEN1 (0.47) | THRBTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL30501021 | 0.87 | HTR2A (0.37) | THRBTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL22059302 | 0.87 | L3MBTL1 (0.41) | THRBTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL25068797 | 0.86 | L3MBTL1 (0.40) | THRBTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL22058245 | 0.86 | L3MBTL1 (0.40) | THRBTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL25121514 | 0.86 | L3MBTL1 (0.40) | THRBTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL15213734 | 0.86 | PDK2 (0.36) | THRBTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL15593130 | 0.86 | L3MBTL1 (0.40) | THRBTDP1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| US-20230225196-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2E1, GPX1, ERCC1 | THRB 3787/4885TDP1 1010/4885KMT2A 2053/4885 |
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2C19, ETV6, ESR1 | THRB 3818/4885TDP1 2899/4885KMT2A 1666/4885 |
| US-20230225196-A1 | MATERIALS FOR ELECTRONIC DEVICES | SELE, EPHA6, EPX | THRB 4524/4885TDP1 933/4885KMT2A 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.