Sugi Predict

Sugi Predict / Compounds / SCHEMBL25818522

SCHEMBL25818522

SCHEMBL25818522

Clc1nc(-c2cccc(-c3ccc4c(-c5ccccc5)cccc4c3)c2)nc(-c2cccc3oc4ccccc4c23)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B1 P14061 1/20 0.36
▸ HSD17B2 P37059 1/20 0.36
▸ BACE1 P56817 1/20 0.36
▸ KDM4E B2RXH2 4/20 0.36
▸ ALDH1A1 P00352 4/20 0.36
▸ ATM Q13315 2/20 0.36
▸ HSD17B10 Q99714 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ MAPT P10636 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ TP53 P04637 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ NFKB1 P19838 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ NFKB2 Q00653 1/20 0.34
▸ RELA Q04206 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25817880 0.94 HSD17B1 (0.40) HSD17B1HSD17B2BACE1KDM4EALDH1A1
SCHEMBL25009004 0.93 CA12 (0.40) HSD17B1HSD17B2BACE1KDM4EALDH1A1
SCHEMBL25132563 0.92 PIM1 (0.38) HSD17B1HSD17B2BACE1KDM4EALDH1A1
SCHEMBL25818437 0.91 ALDH1A1 (0.38) BACE1KDM4EALDH1A1ATMHSD17B10
SCHEMBL25008350 0.91 KDM4E (0.42) HSD17B1HSD17B2BACE1KDM4EALDH1A1
SCHEMBL25818467 0.90 ALDH1A1 (0.37) BACE1KDM4EALDH1A1ATMHSD17B10
SCHEMBL26231377 0.90 ALDH1A1 (0.38) HSD17B1HSD17B2KDM4EALDH1A1ATM
SCHEMBL25818458 0.90 PLA2G2A (0.39) HSD17B1HSD17B2KDM4EALDH1A1ATM
SCHEMBL25008357 0.90 KDM4E (0.39) HSD17B1HSD17B2KDM4EALDH1A1ATM
SCHEMBL22274543 0.90 BACE1 (0.36) HSD17B1HSD17B2BACE1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917914-B1 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-02-27 — — US disclosed
US-20230225206-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-13 — — US disclosed
US-20230225206-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917914-B1 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof NFE2L2, ESR1, OR51E2 HSD17B1 3460/4885HSD17B2 2761/4885BACE1 1406/4885
US-20230225206-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF NFE2L2, ESR1, OR51E2 HSD17B1 3460/4885HSD17B2 2761/4885BACE1 1406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.