Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822152 | 0.89 | PARP10 (0.49) | PARP10PARP15MAOAMAOBBRD4 | |
| SCHEMBL4568914 | 0.85 | PARP10 (0.50) | PARP10PARP15MAOAMAOBBRD4 | |
| SCHEMBL2202355 | 0.84 | PARP10 (0.52) | PARP10PARP15MAOAMAOB | |
| SCHEMBL29819076 | 0.84 | PARP10 (0.52) | PARP10PARP15MAOAMAOB | |
| SCHEMBL25819210 | 0.81 | HTR1B (0.50) | HTR1BCARM1PRMT6NOS3NOS1 | |
| SCHEMBL18721737 | 0.81 | HTR1B (0.50) | HTR1BCARM1PRMT6NOS3NOS1 | |
| SCHEMBL19291642 | 0.81 | HTR1B (0.50) | HTR1BCARM1PRMT6NOS3NOS1 | |
| SCHEMBL2207488 | 0.81 | PARP10 (0.47) | PARP10PARP15BRD4CREBBPKEAP1 | |
| SCHEMBL19291799 | 0.80 | HTR1B (0.51) | HTR1BCARM1PRMT6NOS3NOS1 | |
| SCHEMBL25819231 | 0.79 | KDM4E (0.40) | PARP10PARP15MAOAMAOBHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | PARP10 1846/4885PARP15 2575/4885MAOA 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.