SCHEMBL25819333

SCHEMBL25819333

CCCCc1c2cc(-c3ccc(-c4ccccc4)cc3)cc1Cc1cccc(c1O)Cc1cc(-c3ccc(-c4ccccc4)cc3)cc(c1OCCC)Cc1cccc(c1O)C2

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSTA1 P08263 6/20 0.50
GSTP1 P09211 6/20 0.50
PTPRC P08575 4/20 0.47
PTPN2 P17706 4/20 0.47
PTPN1 P18031 4/20 0.47
PTPRB P23467 4/20 0.47
PTPN11 Q06124 4/20 0.47
CREB1 P16220 1/20 0.36
TLR4 O00206 3/20 0.34
CD14 P08571 3/20 0.34
LY96 Q9Y6Y9 3/20 0.34
SLC13A5 Q86YT5 1/20 0.34
LTB4R Q15722 1/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
HTR2A P28223 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25819205 0.82 GSTA1 (0.55) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL25819329 0.81 GSTA1 (0.53) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL12856732 0.76 GSTA1 (0.67) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL760971 0.75 GSTA1 (0.65) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL23931194 0.74 GSTA1 (0.58) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL25819200 0.74 GSTA1 (0.51) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL19726834 0.73 GSTA1 (0.64) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL12856718 0.73 GSTA1 (0.64) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL761363 0.72 GSTA1 (0.67) GSTA1GSTP1PTPRCPTPN2PTPN1
SCHEMBL14159148 0.70 PTPRC (0.43) GSTA1GSTP1PTPRCPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220158-A1 IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY NATIONAL SCIENCE FOUNDATION 2023-07-13 US disclosed