SCHEMBL25819702

SCHEMBL25819702

CNCCCc1cc(OCC2CCCCC2)cc(C(=O)OCc2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.44
CTSS P25774 2/20 0.42
CTSK P43235 2/20 0.42
CARM1 Q86X55 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
MEN1 O00255 2/20 0.41
CTSL P07711 1/20 0.40
EPHX1 P07099 1/20 0.40
SLC2A1 P11166 1/20 0.40
ACACB O00763 1/20 0.40
ACACA Q13085 1/20 0.40
EPHX2 P34913 2/20 0.39
KAT6A Q92794 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25819727 0.86 PARP10 (0.41) SLC2A1
SCHEMBL19291800 0.77 CHRM2 (0.47) KMT2ACARM1PRMT6MEN1SLC2A1
SCHEMBL2204692 0.77 CHRM2 (0.47) KMT2ACARM1PRMT6MEN1SLC2A1
SCHEMBL25819673 0.77 CHRM2 (0.47) KMT2ACARM1PRMT6MEN1SLC2A1
SCHEMBL25819726 0.77 PARP10 (0.43) SLC2A1
SCHEMBL2208665 0.77 KMT2A (0.37) KMT2AMEN1ACACBACACA
SCHEMBL25819721 0.76 THRA (0.38) CARM1PRMT6SLC2A1ACACBACACA
SCHEMBL25819677 0.76 CHRM2 (0.48) KMT2ACARM1PRMT6MEN1SLC2A1
SCHEMBL4568839 0.75 PARP15 (0.42) SLC2A1
SCHEMBL2204386 0.74 PARP10 (0.44) SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER KMT2A 3008/4885CTSS 3012/4885CTSK 2650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.