Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568841 | 0.86 | CHRNB2 (0.41) | THRATHRBPARP10PARP15CNR1 | |
| SCHEMBL2207625 | 0.83 | PARP10 (0.42) | THRATHRBPARP10PARP15 | |
| SCHEMBL25819727 | 0.82 | PARP10 (0.41) | THRATHRBPARP10PARP15SLC2A1 | |
| SCHEMBL19291800 | 0.81 | CHRM2 (0.47) | CARM1PRMT6SLC2A1ACACBACACA | |
| SCHEMBL25819673 | 0.81 | CHRM2 (0.47) | CARM1PRMT6SLC2A1ACACBACACA | |
| SCHEMBL2204692 | 0.81 | CHRM2 (0.47) | CARM1PRMT6SLC2A1ACACBACACA | |
| SCHEMBL4569120 | 0.81 | PARP10 (0.38) | THRATHRBPARP10PARP15ACACB | |
| SCHEMBL25819677 | 0.80 | CHRM2 (0.48) | CARM1PRMT6SLC2A1ACACBACACA | |
| SCHEMBL25819791 | 0.78 | CHRM2 (0.46) | SIGMAR1CARM1PRMT6SLC2A1ACACB | |
| SCHEMBL25819702 | 0.76 | KMT2A (0.44) | CARM1PRMT6SLC2A1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | THRA 3146/4885THRB 2187/4885SIGMAR1 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.