Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553272 | 0.97 | KDM1A (0.41) | KDM1AKDM1BCES2CES1CA12 | |
| SCHEMBL3838838 | 0.84 | MAPT (0.39) | KDM1AKDM1BCES2CES1CA12 | |
| SCHEMBL29364024 | 0.84 | MAPT (0.39) | KDM1AKDM1BCES2CES1CA12 | |
| SCHEMBL28282385 | 0.84 | KDM1A (0.34) | KDM1AKDM1BCES2CES1CA12 | |
| SCHEMBL9154640 | 0.82 | ALDH1A1 (0.46) | KDM1AKDM1BCES2CES1CA1 | |
| SCHEMBL30350420 | 0.80 | KDM1A (0.34) | KDM1AKDM1BCES2CES1 | |
| SCHEMBL9108244 | 0.80 | KDM1A (0.34) | KDM1AKDM1BCES2CES1 | |
| SCHEMBL8309828 | 0.80 | RAPGEF4 (0.40) | KDM1AKDM1BCES2CES1ALDH1A1 | |
| SCHEMBL4538752 | 0.80 | CA9 (0.44) | KDM1AKDM1BCES2CES1CA12 | |
| SCHEMBL1931981 | 0.79 | KDM1A (0.42) | KDM1AKDM1BAKR1B1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126076-A | Preparation method of 2,4, 6-trifluorobenzyl cyanide | 清源创新实验室 | 2023-11-28 | — | — | CN | claimed |
| CN-117024263-A | Preparation method of 2,4, 6-trifluoro-benzoic acid | 黑龙江立科新材料有限公司 | 2023-11-10 | — | — | CN | claimed |
| EP-3543319-A1 | METHOD OF MARKING HYDROCARBON LIQUIDS | Johnson Matthey Public Limited Company (GB) | 2019-09-25 | — | — | EP | claimed |
| US-20140120626-A1 | METHOD OF MARKING HYDROCARBON LIQUIDS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2014-05-01 | — | — | US | claimed |
| EP-2707465-A1 | METHOD OF MARKING HYDROCARBON LIQUIDS | Johnson Matthey Public Limited Company (GB) | 2014-03-19 | — | — | EP | claimed |
| WO-2012153132-A1 | METHOD OF MARKING HYDROCARBON LIQUIDS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-11-15 | — | — | WO | claimed |
| EP-1362860-B1 | Method for producing tetrakis (fluoraryl)borate magnesium compound | NIPPON CATALYTIC CHEM IND (JP) | 2010-09-15 | — | — | EP | claimed |
| US-7205441-B2 | Method for producing tetrakis (fluoroaryl) borate-magnesium compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-04-17 | — | — | US | claimed |
| CN-1197841-C | Process for producing halogenated phenyl malonic ester | AMERICAN CYANAMID CO (US) | 2005-04-20 | — | — | CN | claimed |
| EP-1002788-B1 | Process for preparing halogenated phenylmalonates | BASF AG (DE) | 2004-03-10 | — | — | EP | claimed |
| US-20030216598-A1 | Method for producing tetrakis ( fluoroaryl) borate-magnesium compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-11-20 | — | — | US | claimed |
| EP-1362860-A1 | Method for producing tetrakis (fluoroaryl) borate magnesium compound | Nippon Shokubai Co., Ltd. (JP) | 2003-11-19 | — | — | EP | claimed |
| US-6156925-A | Process for the preparation of halogenated phenylmaloates | AMERICAN CYANAMID COMPANY (US) | 2000-12-05 | — | — | US | claimed |
| EP-1002788-A1 | Process for preparing halogenated phenylmalonates | American Cyanamid Company (US) | 2000-05-24 | — | — | EP | claimed |
| CN-1250044-A | Process for producing halogenated phenyl malonic ester | AMERICAN CYANAMID CO (US) | 2000-04-12 | — | — | CN | claimed |
| JP-59082323-A | — | — | None | — | — | JP | disclosed |
| JP-59082322-A | — | — | None | — | — | JP | disclosed |
| JP-S5982323-A | TRIFLUOROBENZENE DERIVATIVE | CHISSO CORP | 1984-05-12 | — | — | JP | disclosed |
| JP-S5982322-A | TRIFLUOROBENZENE DERIVATIVE | CHISSO CORP | 1984-05-12 | — | — | JP | disclosed |
| US-4064139-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS, ANTI-PARKINSON'S DISEASE | MERCK & CO., INC. (US) | 1977-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216598-A1 | Method for producing tetrakis ( fluoroaryl) borate-magnesium compound | KRAS, MGAM, CA3 | KDM1A 4098/4885KDM1B 3691/4885CES2 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.