Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 9/20 | 0.39 |
| ▸ | LATS2 | Q9NRM7 | 8/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.39 |
| ▸ | AOC1 | P19801 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23841191 | 0.88 | LOXL2 (0.37) | LATS1LATS2AOC1AOC3PTGDR2 | |
| SCHEMBL30682143 | 0.79 | KDM4C (0.42) | LATS1LATS2KDM4CKDM4AKDM4B | |
| SCHEMBL8277937 | 0.79 | KDM4C (0.46) | LATS1LATS2KDM4CKDM4AKDM4B | |
| SCHEMBL2494065 | 0.78 | LOXL2 (0.58) | LOXL2 | |
| SCHEMBL25819937 | 0.77 | MAPT (0.41) | LOXL2 | |
| SCHEMBL18858537 | 0.77 | AOC1 (0.43) | KDM4CAOC1AOC3PTGDR2KCNH2 | |
| SCHEMBL31734685 | 0.76 | KDM4E (0.46) | LATS1LATS2KDM4CKDM4AKDM4B | |
| SCHEMBL8278971 | 0.74 | KDM4C (0.41) | LATS1LATS2KDM4CKDM4AKDM4B | |
| SCHEMBL15218491 | 0.74 | LMNA (0.49) | KCNH2 | |
| SCHEMBL26664503 | 0.74 | GABRA1 (0.47) | LOXL2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | LATS1 764/4885LATS2 861/4885KDM4C 4652/4885 |
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | LATS1 1192/4885LATS2 1318/4885KDM4C 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.