Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20333040 | 0.88 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL14037653 | 0.86 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL20284982 | 0.86 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL13770430 | 0.83 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL14789140 | 0.83 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL26460947 | 0.83 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL19889810 | 0.83 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL21390263 | 0.83 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL7745275 | 0.81 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL18898243 | 0.79 | CXCR4 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697804-B2 | Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy | POLRMT, HDGF, PCNP | ALDH1A1 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.