Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844606 | 0.79 | S100A9 (0.46) | PIK3CDPIK3CGPIK3CAALDH1A1KMT2A | |
| SCHEMBL799288 | 0.78 | GPR55 (0.42) | PIK3CDPIK3CGPIK3CA | |
| SCHEMBL799116 | 0.78 | CA12 (0.47) | PIK3CDPIK3CGALDH1A1KMT2AMEN1 | |
| SCHEMBL19321631 | 0.77 | APLNR (0.53) | PIK3CDPIK3CGALDH1A1LMNA | |
| SCHEMBL19756420 | 0.76 | IKBKB (0.44) | PIK3CDPIK3CGPIK3CAALDH1A1KMT2A | |
| SCHEMBL578845 | 0.76 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3CAALDH1A1KMT2A | |
| SCHEMBL4637538 | 0.76 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3CAALDH1A1KMT2A | |
| SCHEMBL11665634 | 0.74 | ALDH3A1 (0.43) | PIK3CDPIK3CGPIK3CAALDH1A1KMT2A | |
| SCHEMBL4637536 | 0.74 | MEN1 (0.46) | PIK3CDPIK3CGPIK3CAALDH1A1KMT2A | |
| SCHEMBL19756404 | 0.74 | PIK3C3 (0.40) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | PIK3CD 17/4885PIK3CG 18/4885PIK3CA 7/4885 |
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | PIK3CD 10/4885PIK3CG 13/4885PIK3CA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.