⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287711 | 0.78 | — | — | |
| SCHEMBL18159242 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL22571401 | 0.69 | HTT (0.30) | — | |
| SCHEMBL12091359 | 0.69 | DYRK1A (0.33) | — | |
| SCHEMBL798669 | 0.68 | AHR (0.33) | — | |
| SCHEMBL25848614 | 0.68 | HAVCR2 (0.33) | — | |
| SCHEMBL13086417 | 0.67 | HTR4 (0.31) | — | |
| SCHEMBL24869562 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL13086299 | 0.64 | — | — | |
| SCHEMBL24343697 | 0.64 | DGAT1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |