⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24869562 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL22858219 | 0.78 | — | — | |
| SCHEMBL12026460 | 0.70 | DYRK1A (0.34) | — | |
| SCHEMBL13086736 | 0.69 | — | — | |
| SCHEMBL21282910 | 0.69 | PARP15 (0.33) | — | |
| SCHEMBL19130967 | 0.69 | DGAT1 (0.32) | — | |
| SCHEMBL25848618 | 0.68 | NOS3 (0.32) | — | |
| SCHEMBL13086443 | 0.68 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL10141526 | 0.66 | ACHE (0.44) | — | |
| SCHEMBL13086734 | 0.66 | NPC1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261679-A1 | CSF-1R, Inhibitors, Compositions, and Methods of Use | NOVARTIS AG (CH) | 2010-10-14 | — | — | US | disclosed |