Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29818789 | 0.90 | SMN1; SMN2 (0.51) | NOS3NOS1NOS2TAAR1SMN1; SMN2 | |
| SCHEMBL2206066 | 0.90 | SMN1; SMN2 (0.51) | NOS3NOS1NOS2TAAR1SMN1; SMN2 | |
| SCHEMBL29818723 | 0.90 | TAAR1 (0.48) | NOS3NOS1NOS2TAAR1SLC22A12 | |
| SCHEMBL2205356 | 0.90 | TAAR1 (0.48) | NOS3NOS1NOS2TAAR1SLC22A12 | |
| SCHEMBL25823652 | 0.83 | NPC1 (0.42) | NOS3NOS1NOS2TAAR1SMN1; SMN2 | |
| SCHEMBL25825928 | 0.83 | HTR1B (0.47) | SMN1; SMN2KMT2ASLC22A12DRD2DRD4 | |
| SCHEMBL13881826 | 0.82 | MEN1 (0.44) | NOS3NOS1NOS2TAAR1SMN1; SMN2 | |
| SCHEMBL19291686 | 0.78 | CCNB2 (0.53) | NOS3NOS1NOS2TAAR1KMT2A | |
| SCHEMBL4568939 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2APIK3CDPIK3CA | |
| SCHEMBL9107098 | 0.76 | TAAR1 (0.70) | TAAR1LTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | NOS3 1001/4885NOS1 1659/4885NOS2 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.