Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820557 | 0.83 | NOS3 (0.43) | ALDH1A1LMNADRD2DRD4DRD3 | |
| SCHEMBL25825938 | 0.82 | SLC22A12 (0.46) | KMT2ASLC22A12 | |
| SCHEMBL25825968 | 0.79 | HTT (0.41) | ALDH1A1LMNADRD3SMN1; SMN2KMT2A | |
| SCHEMBL4568939 | 0.75 | SMN1; SMN2 (0.51) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL7059928 | 0.75 | KMT2A (0.67) | HTR1BHTR1DKDM4EALDH1A1LMNA | |
| SCHEMBL25825085 | 0.74 | HTR1B (0.66) | HTR1BHTR1DKDM4EALDH1A1DRD2 | |
| SCHEMBL4568941 | 0.73 | GPBAR1 (0.51) | KDM4ELMNAKMT2ASLC22A12 | |
| SCHEMBL13589881 | 0.73 | ALDH1A1 (0.63) | HTR1BHTR1DKDM4EALDH1A1LMNA | |
| SCHEMBL21601469 | 0.73 | KDM4E (0.58) | HTR1BHTR1DKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL25823626 | 0.73 | CHRM2 (0.49) | SMN1; SMN2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | HTR1B 960/4885HTR1D 1401/4885KDM4E 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.