Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386670 | 1.00 | ALOX15 (0.45) | ALOX15HSD17B10HTTLMNAL3MBTL1 | |
| SCHEMBL24307314 | 0.87 | ALOX15 (0.41) | ALOX15HSD17B10HTTLMNAL3MBTL1 | |
| SCHEMBL25822110 | 0.78 | ALOX15 (0.54) | ALOX15HSD17B10HTTLMNAL3MBTL1 | |
| SCHEMBL21932249 | 0.74 | MAPK1 (0.38) | ALOX15HSD17B10HTTLMNAL3MBTL1 | |
| SCHEMBL31065610 | 0.74 | MAPK1 (0.38) | ALOX15HSD17B10HTTLMNAL3MBTL1 | |
| SCHEMBL25320261 | 0.73 | TNKS (0.32) | ALOX15HSD17B10ALDH1A1IP6K1KDM4E | |
| SCHEMBL707607 | 0.72 | HSD17B10 (0.65) | ALOX15HSD17B10HTTLMNAL3MBTL1 | |
| SCHEMBL707606 | 0.72 | HSD17B10 (0.65) | ALOX15HSD17B10HTTLMNAL3MBTL1 | |
| SCHEMBL707735 | 0.72 | ALOX15 (0.56) | ALOX15HSD17B10HTTLMNAL3MBTL1 | |
| SCHEMBL707736 | 0.72 | ALOX15 (0.56) | ALOX15HSD17B10HTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133413-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-07-13 | — | — | WO | disclosed |