Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FGB | P02675 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26768084 | 0.86 | ALOX15 (0.50) | ALOX15HSD17B10HTTLMNAALDH1A1 | |
| SCHEMBL6069744 | 0.83 | HSD17B10 (0.46) | ALOX15HSD17B10HTTALDH1A1L3MBTL1 | |
| SCHEMBL31386670 | 0.78 | ALOX15 (0.45) | ALOX15HSD17B10HTTLMNAALDH1A1 | |
| SCHEMBL25822020 | 0.78 | ALOX15 (0.45) | ALOX15HSD17B10HTTLMNAALDH1A1 | |
| SCHEMBL6643305 | 0.78 | NOS3 (0.48) | LMNAALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL6642433 | 0.76 | NOS3 (0.44) | TSHRL3MBTL1CHRNB2CHRNA4GAA | |
| SCHEMBL6069470 | 0.75 | ALOX15 (0.38) | ALOX15HSD17B10HTTLMNAALDH1A1 | |
| SCHEMBL12885350 | 0.74 | ALDH1A1 (0.44) | ALOX15HSD17B10HTTLMNAALDH1A1 | |
| SCHEMBL6069808 | 0.73 | NOX1 (0.37) | LMNATSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6645276 | 0.73 | NOS3 (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133413-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-07-13 | — | — | WO | disclosed |