Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822184 | 0.88 | MAPK1 (0.46) | CYP1A2CYP2D6MAPK1CYP2C19KMT2A | |
| SCHEMBL19291579 | 0.87 | HTR1B (0.51) | CYP1A2CYP2D6MAPK1CYP2C19KMT2A | |
| SCHEMBL4568773 | 0.85 | KMT2A (0.49) | MAPK1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL2205886 | 0.84 | TAAR1 (0.46) | MAPK1KMT2ATSHRALDH1A1HIF1A | |
| SCHEMBL25822263 | 0.83 | CYP1A2 (0.51) | CYP1A2CYP2D6MAPK1CYP2C19KMT2A | |
| SCHEMBL25818121 | 0.81 | BCHE (0.43) | CYP2D6MTNR1AMTNR1B | |
| SCHEMBL25822241 | 0.80 | TSHR (0.61) | CYP1A2CYP2D6MAPK1CYP2C19KMT2A | |
| SCHEMBL13881687 | 0.80 | CYP1A2 (0.42) | CYP1A2CYP2D6MAPK1CYP2C19KMT2A | |
| SCHEMBL25822212 | 0.80 | MTNR1A (0.44) | MTNR1AMTNR1BKDM4ENSD2ALDH1A1 | |
| SCHEMBL25818089 | 0.80 | MTNR1A (0.44) | MTNR1AMTNR1BKDM4ENSD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | CYP1A2 2835/4885CYP2D6 3632/4885MAPK1 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.