Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822263 | 0.90 | CYP1A2 (0.51) | TSHRKMT2ACYP2D6CYP1A2MAPK1 | |
| SCHEMBL25822227 | 0.87 | CYP1A2 (0.65) | TSHRKMT2ACYP2D6CYP1A2MAPK1 | |
| SCHEMBL11663051 | 0.86 | TSHR (0.72) | TSHRKMT2ASMPD1PLA2G4BGPBAR1 | |
| SCHEMBL25822245 | 0.85 | HTR1B (0.59) | TSHRKMT2ACYP2D6CYP1A2MAPK1 | |
| SCHEMBL6677146 | 0.84 | TSHR (0.76) | TSHRSMPD1PLA2G4BGPBAR1LTA4H | |
| SCHEMBL4208924 | 0.84 | TSHR (0.76) | TSHRSMPD1PLA2G4BGPBAR1LTA4H | |
| SCHEMBL16699620 | 0.84 | TSHR (0.76) | TSHRSMPD1PLA2G4BGPBAR1LTA4H | |
| SCHEMBL17138169 | 0.84 | TSHR (0.76) | TSHRSMPD1PLA2G4BGPBAR1LTA4H | |
| SCHEMBL3905859 | 0.84 | TSHR (0.76) | TSHRSMPD1PLA2G4BGPBAR1LTA4H | |
| SCHEMBL17138159 | 0.84 | TSHR (0.76) | TSHRSMPD1PLA2G4BGPBAR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | TSHR 2971/4885KMT2A 3008/4885CYP2D6 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.