Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Diisopentoxybenzene SCHEMBL2846359 | 0.86 | TDP1 (0.57) | GALR3HSP90AA1TDP1NR1H4KDM4E | |
| SCHEMBL13881797 | 0.85 | HTR1B (0.58) | GALR3HSP90AA1TDP1NR1H4KDM4E | |
| SCHEMBL25818187 | 0.82 | AOC3 (0.50) | GALR3HSP90AA1TDP1NR1H4KDM4E | |
| SCHEMBL29819005 | 0.81 | TDP1 (0.53) | GALR3HSP90AA1TDP1NR1H4MAPK1 | |
| SCHEMBL2208810 | 0.81 | TDP1 (0.53) | GALR3HSP90AA1TDP1NR1H4MAPK1 | |
| SCHEMBL25822263 | 0.81 | CYP1A2 (0.51) | NR1H4KDM4ENSD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL25822276 | 0.80 | MAPK1 (0.58) | KDM4EALDH1A1MAPK1CYP1A2CYP2D6 | |
| 3-Propoxy-1-Isopentoxybenzene SCHEMBL2839921 | 0.80 | KMT2A (0.51) | GALR3HSP90AA1TDP1NR1H4KDM4E | |
| 1-Isopentyloxy-3-Ethoxybenzene SCHEMBL2840066 | 0.80 | MAPK1 (0.53) | GALR3HSP90AA1TDP1NR1H4KDM4E | |
| 1-Isopentyloxy-3-Methoxybenzene SCHEMBL791293 | 0.80 | NPSR1 (0.58) | GALR3HSP90AA1TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | GALR3 101/4885HSP90AA1 2896/4885TDP1 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.