Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208810 | 1.00 | TDP1 (0.53) | TDP1TAAR1GALR3HSP90AA1NR1H4 | |
| 1,3-Diisopentoxybenzene SCHEMBL2846359 | 0.91 | TDP1 (0.57) | TDP1GALR3HSP90AA1NR1H4MAPK1 | |
| SCHEMBL18293491 | 0.86 | TAAR1 (0.48) | TDP1TAAR1GALR3HSP90AA1LTA4H | |
| SCHEMBL9107098 | 0.84 | TAAR1 (0.70) | TAAR1LTA4HPLA2G2AMAPK1 | |
| 1-Isopentyloxy-3-Ethoxybenzene SCHEMBL2840066 | 0.84 | MAPK1 (0.53) | TDP1GALR3HSP90AA1NR1H4MAPK1 | |
| 1-Isopentyloxy-3-Methoxybenzene SCHEMBL791293 | 0.84 | NPSR1 (0.58) | TDP1GALR3HSP90AA1MAPK1MEN1 | |
| 3-Propoxy-1-Isopentoxybenzene SCHEMBL2839921 | 0.84 | KMT2A (0.51) | TDP1GALR3HSP90AA1NR1H4MAPK1 | |
| SCHEMBL28032739 | 0.83 | TAAR1 (0.58) | TDP1TAAR1GALR3HSP90AA1NR1H4 | |
| SCHEMBL26850251 | 0.83 | TAAR1 (0.50) | TDP1TAAR1LTA4HPLA2G2AMAPK1 | |
| SCHEMBL19553486 | 0.83 | TDP1 (0.50) | TDP1TAAR1GALR3HSP90AA1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029708-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-11446261-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12029708-B2 | Alkoxy compounds for disease treatment | ALDH1A2, CLN6, AGER | TDP1 499/4885TAAR1 1482/4885GALR3 100/4885 |
| US-11446261-B2 | Alkoxy compounds for disease treatment | ALDH1A2, CLN6, AGER | TDP1 499/4885TAAR1 1482/4885GALR3 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.