Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | GALR3 | O60755 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Isopentyloxy-3-Methoxybenzene SCHEMBL791293 | 0.92 | NPSR1 (0.58) | TDP1GALR3HSP90AA1MAPK1MEN1 | |
| 1-Isopentyloxy-3-Ethoxybenzene SCHEMBL2840066 | 0.92 | MAPK1 (0.53) | TDP1GALR3HSP90AA1NR1H4MAPK1 | |
| 3-Propoxy-1-Isopentoxybenzene SCHEMBL2839921 | 0.92 | KMT2A (0.51) | TDP1GALR3HSP90AA1NR1H4MAPK1 | |
| SCHEMBL2843423 | 0.91 | TDP1 (0.53) | TDP1GALR3HSP90AA1MAPK1KMT2A | |
| SCHEMBL2208810 | 0.91 | TDP1 (0.53) | TDP1GALR3HSP90AA1NR1H4MAPK1 | |
| SCHEMBL19291689 | 0.91 | GALR3 (0.49) | TDP1GALR3HSP90AA1NR1H4MAPK1 | |
| SCHEMBL29819005 | 0.91 | TDP1 (0.53) | TDP1GALR3HSP90AA1NR1H4MAPK1 | |
| SCHEMBL19806820 | 0.89 | MAPK1 (0.50) | TDP1GALR3HSP90AA1MAPK1MEN1 | |
| SCHEMBL7144506 | 0.88 | SMN1; SMN2 (0.54) | TDP1GALR3HSP90AA1MAPK1KMT2A | |
| SCHEMBL29690388 | 0.88 | SMN1; SMN2 (0.54) | TDP1GALR3HSP90AA1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9497963-B2 | Methods and compositions for control of gypsy moth, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2016-11-22 | — | — | US | disclosed |
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | RNS CO.,LTD. (KR) | 2015-10-08 | — | — | US | disclosed |
| US-9125406-B2 | Methods and compositions for control of cabbage looper, trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2015-09-08 | — | — | US | disclosed |
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-23 | — | — | US | disclosed |
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2013-02-21 | — | — | US | disclosed |
| US-20100297059-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR | SIMON FRASER UNIVERSITY (CA) | 2010-11-25 | — | — | US | disclosed |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | SIMON FRASER UNIVERSITY (CA) | 2010-07-29 | — | — | US | disclosed |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2010-06-24 | — | — | US | disclosed |
| US-20090118169-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-7314888-B1 | Compounds and medicinal use thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| EP-1127869-A1 | NOVEL COMPOUNDS AND MEDICINAL USE THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-4125512-A | RESORCINOL DONOR, FORMALDEHYDE DONOR, CALCIUM SILICATE, GROUP 2A OR 3A METAL OXIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | CDV3, ETV1, BOLA2; BOLA2B | TDP1 3012/4885GALR3 2122/4885HSP90AA1 1620/4885 |
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | TDP1 1624/4885GALR3 14/4885HSP90AA1 3129/4885 |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | TDP1 1252/4885GALR3 13/4885HSP90AA1 3032/4885 |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | CDV3, ETV1, TMSB4X | TDP1 3110/4885GALR3 2076/4885HSP90AA1 1715/4885 |
| US-20100297059-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR | L3MBTL3, L3MBTL4, L3MBTL1 | TDP1 1255/4885GALR3 13/4885HSP90AA1 2994/4885 |
| US-20150283051-A1 | DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF | HRH3, CBR3, H1-0 | TDP1 3517/4885GALR3 335/4885HSP90AA1 3014/4885 |
| US-20090118169-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | SP1, AP1G1, AP1M1 | TDP1 2551/4885GALR3 2839/4885HSP90AA1 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.