Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822233 | 0.97 | CYP1A2 (0.65) | CYP1A2CYP2D6MAPK1CYP2C19KDM4E | |
| SCHEMBL25822276 | 0.92 | MAPK1 (0.58) | CYP1A2CYP2D6MAPK1CYP2C19KDM4E | |
| SCHEMBL25822241 | 0.87 | TSHR (0.61) | CYP1A2CYP2D6MAPK1CYP2C19KMT2A | |
| SCHEMBL25822229 | 0.85 | CYP1A2 (0.67) | CYP1A2CYP2D6MAPK1CYP2C19KDM4E | |
| SCHEMBL25821806 | 0.83 | KDM4E (0.56) | CYP1A2CYP2D6MAPK1CYP2C19KDM4E | |
| SCHEMBL25822263 | 0.83 | CYP1A2 (0.51) | CYP1A2CYP2D6MAPK1CYP2C19KDM4E | |
| SCHEMBL19291509 | 0.81 | CYP1A2 (0.67) | CYP1A2CYP2D6MAPK1CYP2C19KDM4E | |
| SCHEMBL29818899 | 0.81 | MAPK1 (0.57) | CYP1A2CYP2D6MAPK1CYP2C19KDM4E | |
| SCHEMBL2206381 | 0.81 | MAPK1 (0.57) | CYP1A2CYP2D6MAPK1CYP2C19KDM4E | |
| SCHEMBL11455127 | 0.79 | DRD2 (0.64) | MAPK1KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | CYP1A2 2835/4885CYP2D6 3632/4885MAPK1 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.