Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.54 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.54 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24581748 | 0.85 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1PRSS1ALDH1A1 | |
| SCHEMBL27311375 | 0.85 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1PRSS1ALDH1A1 | |
| SCHEMBL8426731 | 0.84 | ALDH1A1 (0.60) | TPSAB1TPSD1TPSG1PRSS1ALDH1A1 | |
| SCHEMBL20160133 | 0.84 | TOP2A (0.49) | ALDH1A1CYP3A4LMNANPSR1SMN1; SMN2 | |
| SCHEMBL18430370 | 0.83 | L3MBTL1 (0.45) | TPSAB1TPSD1TPSG1PRSS1ALDH1A1 | |
| SCHEMBL17232558 | 0.80 | SMN1; SMN2 (0.49) | TPSAB1TPSD1TPSG1PRSS1LMNA | |
| SCHEMBL25823048 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4LMNANPSR1SMN1; SMN2 | |
| SCHEMBL17448403 | 0.79 | SMN1; SMN2 (0.48) | TPSAB1TPSD1TPSG1PRSS1LMNA | |
| SCHEMBL24760536 | 0.79 | ALDH1A1 (0.44) | TPSAB1PRSS1ALDH1A1LMNACTSL | |
| SCHEMBL19154486 | 0.79 | SMN1; SMN2 (0.48) | TPSAB1TPSD1TPSG1PRSS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883926-B1 | BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDE DERIVATIVES AND PROTEIN CONJUGATES THEREOF FOR USE AS LXR AGONISTS | REGENERON PHARMA (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023129518-A1 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |