Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD5 | P21918 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12788915 | 0.81 | TSHR (0.69) | MAPK1TAAR1TSHRLMNAGLA | |
| SCHEMBL29365033 | 0.78 | TAAR1 (1.00) | MAPK1TAAR1TSHRLMNAGLA | |
| SCHEMBL68386 | 0.78 | TAAR1 (1.00) | MAPK1TAAR1TSHRLMNAGLA | |
| Hydrochloric Acid SCHEMBL347598 | 0.76 | TAAR1 (1.00) | MAPK1TAAR1TSHRLMNAGLA | |
| Hydrochloric Acid SCHEMBL7360734 | 0.75 | TAAR1 (0.77) | MAPK1TAAR1TSHRLMNAGLA | |
| Hydrochloric Acid SCHEMBL15845572 | 0.75 | TAAR1 (0.93) | MAPK1TAAR1TSHRLMNAGLA | |
| SCHEMBL21709064 | 0.74 | TAAR1 (0.58) | MAPK1TAAR1TSHRLMNAGLA | |
| SCHEMBL14213279 | 0.74 | TSHR (0.62) | MAPK1TAAR1TSHRLMNAGLA | |
| SCHEMBL23309939 | 0.73 | TAAR1 (0.67) | MAPK1TAAR1TSHRLMNAGLA | |
| Deoxiepinephrine SCHEMBL14918907 | 0.73 | MAPT (0.83) | MAPK1TAAR1TSHRLMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218768-A1 | Chemically Coupled Transporter for Low-Hydrophobicity Bioactive Drugs into the Central Nervous System | CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET) (AR) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218768-A1 | Chemically Coupled Transporter for Low-Hydrophobicity Bioactive Drugs into the Central Nervous System | SLC6A3, SLC18A2, TSPO | MAPK1 2450/4885TAAR1 756/4885TSHR 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.