Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899048 | 0.88 | SIRT2 (0.47) | SLC2A1SIRT2ADAM17ACACBACACA | |
| SCHEMBL4568858 | 0.88 | SLC2A1 (0.52) | SLC2A1SIRT2ADAM17ACACBACACA | |
| SCHEMBL29818757 | 0.84 | SIRT2 (0.50) | SLC2A1SIRT2ADAM17PARP10PARP15 | |
| SCHEMBL2205210 | 0.84 | SIRT2 (0.50) | SLC2A1SIRT2ADAM17PARP10PARP15 | |
| SCHEMBL4569164 | 0.84 | SLC2A1 (0.44) | SLC2A1SIRT2ADAM17ACACBACACA | |
| SCHEMBL7312468 | 0.82 | THRA (0.58) | SLC2A1SIRT2PARP10PARP15TLR4 | |
| SCHEMBL13881838 | 0.81 | SLC2A1 (0.49) | SLC2A1SIRT2ADAM17ACACBACACA | |
| SCHEMBL25818867 | 0.81 | HTR2C (0.50) | SLC2A1SIRT2ADAM17ACACBACACA | |
| SCHEMBL7316033 | 0.80 | POLB (0.52) | SLC2A1SIRT2ADAM17ACACBACACA | |
| SCHEMBL1295204 | 0.77 | KDM5A (0.42) | SLC2A1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | SLC2A1 891/4885SIRT2 903/4885ADAM17 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.