SCHEMBL25823479

SCHEMBL25823479

C=C(CCC)C(=O)Oc1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 3/20 0.54
PGR P06401 1/20 0.54
GAA P10253 1/20 0.54
PTGS1 P23219 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MEN1 O00255 1/20 0.49
RAB9A P51151 1/20 0.49
TSHR P16473 1/20 0.48
KDM4E B2RXH2 3/20 0.47
HPGD P15428 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
MMP2 P08253 1/20 0.43
OGG1 O15527 1/20 0.43
HTR1B P28222 1/20 0.43
FABP7 O15540 3/20 0.43
FABP3 P05413 3/20 0.43
FABP5 Q01469 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1336289 0.89 ALDH1A1 (0.55) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL5402020 0.84 ALDH1A1 (0.53) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL18832076 0.84 ALDH1A1 (0.47) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL4830574 0.83 ALDH1A1 (0.51) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL29373398 0.82 ALDH1A1 (0.58) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL447135 0.82 ALDH1A1 (0.58) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL7181428 0.81 ALDH1A1 (0.65) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL1949303 0.81 GAA (0.43) HSD17B10GAAKMT2AMEN1TSHR
Butane SCHEMBL8966575 0.81 ALDH1A1 (0.57) ALDH1A1HSD17B10PGRGAAPTGS1
SCHEMBL28008688 0.81 THRA (0.44) HSD17B10KMT2AL3MBTL1MEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212136-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT, DIFFRACTIVE OPTICAL ELEMENT, AND MULTILAYER DIFFRACTIVE OPTICAL ELEMENT FUJIFILM CORPORATION (JP) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212136-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT, DIFFRACTIVE OPTICAL ELEMENT, AND MULTILAYER DIFFRACTIVE OPTICAL ELEMENT TERB1, RER1, LARP1 ALDH1A1 228/4885HSD17B10 4723/4885PGR 825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.