Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18611816 | 0.87 | ACACB (0.45) | ALDH1A1HPGDGAAACACBACACA | |
| SCHEMBL20133300 | 0.86 | ACACB (0.43) | ALDH1A1HPGDGAAACACBACACA | |
| SCHEMBL20372470 | 0.85 | ACACB (0.46) | PLA2G4BHPGDACACBACACALMNA | |
| SCHEMBL25823802 | 0.84 | PLA2G4B (0.40) | PLA2G4BPOLBALDH1A1HPGDGAA | |
| SCHEMBL24675646 | 0.84 | PLA2G4B (0.48) | PLA2G4BPOLBALDH1A1TSHRTDP1 | |
| SCHEMBL25823398 | 0.84 | PLA2G4B (0.48) | PLA2G4BPOLBALDH1A1TSHRTDP1 | |
| SCHEMBL24675644 | 0.84 | PLA2G4B (0.48) | PLA2G4BPOLBALDH1A1TSHRTDP1 | |
| SCHEMBL18591857 | 0.84 | ALDH1A1 (0.51) | PLA2G4BPOLBALDH1A1TSHRTDP1 | |
| SCHEMBL18551111 | 0.80 | ITGB3 (0.46) | ALDH1A1TSHRHPGDGAAACACB | |
| SCHEMBL18551103 | 0.80 | ITGB3 (0.46) | ALDH1A1TSHRHPGDGAAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129564-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |