Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824069 | 0.85 | ALDH1A1 (0.39) | ALDH1A1GRM5SMN1; SMN2BLM | |
| SCHEMBL25824066 | 0.85 | ALDH1A1 (0.39) | ALDH1A1GRM5SMN1; SMN2BLM | |
| SCHEMBL25824071 | 0.72 | CDA (0.38) | — | |
| SCHEMBL26233448 | 0.65 | RNASE1 (0.42) | ALDH1A1RNASE1POLBCYP1A2 | |
| SCHEMBL30063016 | 0.61 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KMT2ABLMMAPT | |
| SCHEMBL14929485 | 0.61 | CDA (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2ABLM | |
| SCHEMBL23215397 | 0.60 | RNASE1 (0.47) | ALDH1A1RNASE1POLBMEN1KMT2A | |
| SCHEMBL23240761 | 0.60 | RNASE1 (0.47) | ALDH1A1RNASE1POLBMEN1KMT2A | |
| SCHEMBL9908701 | 0.60 | RNASE1 (0.44) | RNASE1 | |
| SCHEMBL767866 | 0.60 | RNASE1 (0.44) | RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |