Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824069 | 1.00 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2BLMSLC18A3GRM5 | |
| SCHEMBL25824070 | 0.85 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2BLMGRM5 | |
| SCHEMBL23216844 | 0.79 | TYMP (0.43) | ALDH1A1SMN1; SMN2BLM | |
| SCHEMBL26233449 | 0.71 | RNASE1 (0.42) | — | |
| SCHEMBL25824051 | 0.70 | CDA (0.47) | SMN1; SMN2 | |
| SCHEMBL12404713 | 0.65 | POLB (0.66) | — | |
| SCHEMBL30063016 | 0.65 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2BLM | |
| SCHEMBL14929485 | 0.65 | CDA (0.35) | ALDH1A1SMN1; SMN2BLM | |
| SCHEMBL21563855 | 0.64 | RNASE1 (0.48) | SMN1; SMN2BLM | |
| SCHEMBL537189 | 0.64 | RNASE1 (0.48) | SMN1; SMN2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |