Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | NT5C2 | P49902 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673049 | 0.92 | ADK (0.46) | BRD4ADKADORA3ADORA2ACSF1R | |
| SCHEMBL23215743 | 0.92 | ADK (0.46) | BRD4ADKADORA3ADORA2ACSF1R | |
| SCHEMBL27056716 | 0.86 | ADORA2B (0.40) | ADKADORA3ADORA2A | |
| SCHEMBL29709101 | 0.83 | TYMP (0.45) | BRD4ADORA3ADORA2A | |
| SCHEMBL23215660 | 0.83 | TYMP (0.45) | BRD4ADORA3ADORA2A | |
| SCHEMBL23215200 | 0.83 | TYMP (0.45) | BRD4ADORA3ADORA2A | |
| SCHEMBL29709093 | 0.83 | TYMP (0.45) | BRD4ADORA3ADORA2A | |
| SCHEMBL26782168 | 0.81 | ADK (0.49) | ADKADORA3ADORA2A | |
| SCHEMBL3619552 | 0.81 | HIF1A (0.43) | ADKADORA3ADORA2A | |
| SCHEMBL3619557 | 0.81 | HIF1A (0.43) | ADKADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |