Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 7/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | GAPDH | P04406 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.50 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27056585 | 1.00 | ADK (0.59) | ADKADORA3ADORA2AHSD17B10GAPDH | |
| SCHEMBL23216880 | 0.87 | CYP1A2 (0.57) | ADKADORA3ADORA2AHSD17B10GAPDH | |
| SCHEMBL29673052 | 0.87 | CYP1A2 (0.57) | ADKADORA3ADORA2AHSD17B10GAPDH | |
| SCHEMBL25824126 | 0.84 | ADORA3 (0.49) | ADKADORA3ADORA2AADORA1 | |
| SCHEMBL6909853 | 0.83 | LMNA (0.72) | ADORA3ADORA2ASLC29A1ADORA1 | |
| SCHEMBL17889837 | 0.83 | LMNA (0.72) | ADORA3ADORA2ASLC29A1ADORA1 | |
| SCHEMBL9945526 | 0.83 | LMNA (0.72) | ADORA3ADORA2ASLC29A1ADORA1 | |
| SCHEMBL21953578 | 0.83 | LMNA (0.72) | ADORA3ADORA2ASLC29A1ADORA1 | |
| SCHEMBL19485512 | 0.83 | LMNA (0.72) | ADORA3ADORA2ASLC29A1ADORA1 | |
| SCHEMBL313413 | 0.83 | LMNA (0.72) | ADORA3ADORA2ASLC29A1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |