SCHEMBL25824930

SCHEMBL25824930

CC(C)(C)C1CC2(C1)CN(C(=O)C1CCCC1)C2

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 9/20 0.49
GRM5 P41594 1/20 0.45
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
MGLL Q99685 2/20 0.39
LMNA P02545 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
CHRNB3 Q05901 1/20 0.39
CHRNA6 Q15825 1/20 0.39
HSD11B2 P80365 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24007484 0.77 SMN1; SMN2 (0.44) HSD11B1ALDH1A1TSHRCHRNB2CHRNA3
SCHEMBL19398108 0.75 ALDH1A1 (0.61) HSD11B1ALDH1A1TSHRLMNASMN1; SMN2
SCHEMBL19398107 0.74 ALDH1A1 (0.64) HSD11B1ALDH1A1TSHRLMNAHSD11B2
SCHEMBL24043985 0.72 ALDH1A1 (0.52) HSD11B1ALDH1A1TSHRLMNACHRNB2
SCHEMBL25810397 0.72 HSD11B1 (0.61) HSD11B1GRM5ALDH1A1TSHRLMNA
SCHEMBL25810400 0.72 HSD11B1 (0.66) HSD11B1GRM5ALDH1A1TSHRLMNA
SCHEMBL19398106 0.72 HSD11B1 (0.58) HSD11B1ALDH1A1TSHRLMNACHRNB2
SCHEMBL16075008 0.71 BTK (0.36)
SCHEMBL26738602 0.71 EPHX2 (0.42) SMN1; SMN2
SCHEMBL18390027 0.71 LMNA (0.56) HSD11B1GRM5ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125737-A1 HETEROCYCLIC COMPOUNDS AND USE THEREOF SILEXON AI TECHNOLOGY CO., LTD. (CN) 2023-07-06 WO disclosed