Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912550 | 0.85 | LIPE (0.54) | SMN1; SMN2ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL11625128 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL4741073 | 0.81 | MMP2 (0.46) | SMN1; SMN2ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL12132475 | 0.81 | FAAH (0.52) | ALDH1A1KDM4EHPGDMMP2MAPT | |
| SCHEMBL1895598 | 0.81 | SLC1A3 (0.57) | SMN1; SMN2ALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL1714626 | 0.80 | LMNA (0.59) | SMN1; SMN2ALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL5699582 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL12132472 | 0.79 | GAA (0.53) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13992390 | 0.79 | TRPV1 (0.51) | SMN1; SMN2ALDH1A1KDM4ERAB9AKMT2A | |
| Hydrogen Peroxide SCHEMBL9578945 | 0.79 | LMNA (0.57) | SMN1; SMN2ALDH1A1KDM4ERAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | SMN1; SMN2 2070/4885ALDH1A1 4541/4885KDM4E 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.