Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999489 | 0.94 | MAPT (0.53) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL9480270 | 0.91 | ALDH1A1 (0.72) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL589501 | 0.89 | ALDH1A1 (0.65) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL5177511 | 0.89 | ALDH1A1 (0.65) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL24003957 | 0.88 | MAPT (0.49) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL9480551 | 0.87 | ALDH1A1 (0.72) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL15140688 | 0.83 | PORCN (0.64) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL9480171 | 0.83 | ALDH1A1 (0.67) | ALDH1A1GAAHTTSMN1; SMN2MAPT | |
| SCHEMBL25825682 | 0.80 | TAAR1 (0.85) | GAAHTTSMN1; SMN2MAPTRAB9A | |
| Phenyl Phenylcarbamate SCHEMBL272994 | 0.80 | ALDH1A1 (0.76) | ALDH1A1GAAHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | ALDH1A1 4541/4885GAA 819/4885HTT 2703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.