SCHEMBL589501

SCHEMBL589501

O=C(Nc1ccncc1)Oc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
MAPT P10636 4/20 0.65
RAD51 Q06609 1/20 0.63
GAA P10253 3/20 0.60
HTT P42858 2/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
KMT2A Q03164 4/20 0.59
KDM4E B2RXH2 3/20 0.59
LMNA P02545 2/20 0.59
MEN1 O00255 2/20 0.59
THRB P10828 1/20 0.59
GFER P55789 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
POLB P06746 1/20 0.59
TAAR1 Q96RJ0 1/20 0.59
TP53 P04637 1/20 0.58
JAK2 O60674 1/20 0.56
TYK2 P29597 1/20 0.56
RAB9A P51151 1/20 0.55
TSHR P16473 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5177511 0.93 ALDH1A1 (0.65) ALDH1A1MAPTRAD51GAAHTT
SCHEMBL15140688 0.90 PORCN (0.64) ALDH1A1MAPTRAD51GAAHTT
SCHEMBL25825689 0.89 ALDH1A1 (0.60) ALDH1A1MAPTRAD51GAAHTT
SCHEMBL8063648 0.87 ALDH1A1 (0.82) ALDH1A1MAPTRAD51GAAHTT
Phenyl Phenylcarbamate SCHEMBL272994 0.87 ALDH1A1 (0.76) ALDH1A1MAPTRAD51GAAHTT
SCHEMBL6962290 0.85 CYP1A2 (0.65) HTTSMN1; SMN2KMT2AKDM4ELMNA
SCHEMBL23999489 0.84 MAPT (0.53) ALDH1A1MAPTRAD51GAAHTT
SCHEMBL27714666 0.83 GALR3 (0.57) ALDH1A1MAPTGAAHTTSMN1; SMN2
SCHEMBL28109363 0.83 LMNA (0.49) ALDH1A1MAPTRAD51GAAHTT
SCHEMBL7538948 0.83 KMT2A (0.62) ALDH1A1GAAHTTSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101698-A1 HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF PROTAGONIST THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-07-31 US disclosed
US-12291515-B2 Pyrrolidine derivative and use thereof WANG, Zheming (CN) 2025-05-06 US disclosed
US-12269800-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2025-04-08 US disclosed
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-02-13 US disclosed
CN-113923988-B Substituted arylmethyl ureas and heteroarylmethyl ureas, analogs thereof, and methods of using the same 爱彼特生物制药公司 2024-12-13 CN disclosed
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2024-07-25 US disclosed
US-20240216355-A1 PHARMACEUTICAL COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF A DISEASE OR DISORDER CAUSED BY OR ASSOCIATED WITH ONE OR MORE PREMATURE TERMINATION CODONS MONTE ROSA THERAPEUTICS AG (CH) 2024-07-04 US disclosed
US-11999694-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2024-06-04 US disclosed
EP-3893645-B1 SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME ARBUTUS BIOPHARMA CORP (CA) 2024-04-17 EP disclosed
EP-1159258-A1 AMIDE COMPOUNDS FOR THE POTENTIATION OF CHOLINERGIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-12-05 EP disclosed
WO-2000051970-A1 AMIDE COMPOUNDS FOR THE POTENTIATION OF CHOLINERGIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-09-08 WO disclosed
US-6008230-A TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-12-28 US disclosed
US-5994368-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-30 US disclosed
CN-1168667-A Pyridopyrimidones, quinolines and fused N-heretocycles as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO (JP) 1997-12-24 CN disclosed
EP-0807105-A1 PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-19 EP disclosed
WO-1996013485-A1 PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-05-09 WO disclosed
EP-0168005-B1 SEMICARBAZIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-04-18 EP disclosed
US-4694004-A ANALGESICS; ANTIINFLAMMATORY AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-09-15 US disclosed
EP-0168005-A2 Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT ALDH1A1 1109/4885MAPT 2002/4885RAD51 4276/4885
US-20240216355-A1 PHARMACEUTICAL COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF A DISEASE OR DISORDER CAUSED BY OR ASSOCIATED WITH ONE OR MORE PREMATURE TERMINATION CODONS UPF1, NSUN2, RTF2 ALDH1A1 4150/4885MAPT 4671/4885RAD51 3229/4885
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT ALDH1A1 1109/4885MAPT 2002/4885RAD51 4276/4885
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT ALDH1A1 1109/4885MAPT 2002/4885RAD51 4276/4885
US-12269800-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT ALDH1A1 1109/4885MAPT 2002/4885RAD51 4276/4885
US-11999694-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT ALDH1A1 1109/4885MAPT 2002/4885RAD51 4276/4885
US-12291515-B2 Pyrrolidine derivative and use thereof NAMPT, NAPRT, NNMT ALDH1A1 1525/4885MAPT 1410/4885RAD51 4239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.