Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999785 | 0.90 | MAPT (0.54) | MAPKAPK2MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30180392 | 0.90 | MAPT (0.54) | MAPKAPK2MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL24006299 | 0.83 | DNMT1 (0.56) | MAPKAPK2MAPTRAB9ASMN1; SMN2SLC2A1 | |
| SCHEMBL30180296 | 0.83 | MAPT (0.48) | MAPKAPK2MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23999596 | 0.83 | MAPT (0.48) | MAPKAPK2MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23999911 | 0.82 | MAPKAPK2 (0.57) | MAPKAPK2MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL23999914 | 0.81 | MAPKAPK2 (0.55) | MAPKAPK2MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL24005997 | 0.80 | MAPKAPK2 (0.47) | MAPKAPK2MAPTRAB9ASMN1; SMN2SLC2A1 | |
| SCHEMBL25825681 | 0.80 | MAPT (0.56) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL25826014 | 0.79 | MAPKAPK2 (0.47) | MAPKAPK2MAPTALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MAPKAPK2 138/4885MAPT 3999/4885ALDH1A1 4541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.