Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 5/20 | 0.43 |
| ▸ | PDE2A | O00408 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25849033 | 0.87 | FDPS (0.41) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL21311452 | 0.87 | FDPS (0.41) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL30544611 | 0.84 | ADA (0.62) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL1742884 | 0.84 | ADA (0.62) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL17017279 | 0.84 | ADA (0.62) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL22571187 | 0.82 | ADORA2A (0.53) | CYP3A4KDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL29782897 | 0.82 | ADA (0.40) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL21311457 | 0.78 | ADA (0.39) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL7155208 | 0.78 | FDPS (0.39) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL29782912 | 0.76 | FDPS (0.41) | ADAPDE2ACYP3A4PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |