Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ADA | P00813 | 5/20 | 0.41 |
| ▸ | PDE2A | O00408 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311452 | 1.00 | FDPS (0.41) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL29782897 | 0.94 | ADA (0.40) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL29782912 | 0.88 | FDPS (0.41) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL25826138 | 0.87 | ADA (0.43) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL17017279 | 0.83 | ADA (0.62) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL30544611 | 0.83 | ADA (0.62) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL7155208 | 0.80 | FDPS (0.39) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL21311362 | 0.77 | ADA (0.36) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL19661553 | 0.77 | ADA (0.36) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL25849034 | 0.77 | ADA (0.35) | FDPSADAPDE2ACYP3A4PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708381-B2 | Inhibitors of androgen receptor signaling | XAVIER UNIVERSITY OF LOUISIANA (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708381-B2 | Inhibitors of androgen receptor signaling | AR, ESRRA, ESRRB | FDPS 2307/4885ADA 3530/4885PDE2A 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.