Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 5/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311452 | 0.80 | FDPS (0.41) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL25849033 | 0.80 | FDPS (0.41) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL11904867 | 0.80 | FDPS (0.40) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL29782912 | 0.79 | FDPS (0.41) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL25826138 | 0.78 | ADA (0.43) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL17017279 | 0.77 | ADA (0.62) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL30544611 | 0.77 | ADA (0.62) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL29782897 | 0.77 | ADA (0.40) | FDPSADAPDE2ACYP3A4PDE4A | |
| SCHEMBL27854933 | 0.73 | FDPS (0.40) | FDPSCYP3A4ALDH1A1CYP1A2TSHR | |
| SCHEMBL1742009 | 0.72 | FDPS (0.58) | FDPSADAPDE2ACYP3A4PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030022864-A1 | 9-[(5-dihydroxyboryl)-pentyl] purines, useful as an inhibitor of inflammatory cytokines | LEUKOMED, INC. | 2003-01-30 | — | — | US | disclosed |
| US-20030022864-A1 | 9-[(5-dihydroxyboryl)-pentyl] purines, useful as an inhibitor of inflammatory cytokines | LEUKOMED, INC. | 2003-01-30 | — | — | US | disclosed |
| WO-2002085916-A1 | 9-[(5-DIHYDROXYBORYL)-PENTYL] PURINES, INHIBITOR OF INFLAMMATORY CYTOKINES | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022864-A1 | 9-[(5-dihydroxyboryl)-pentyl] purines, useful as an inhibitor of inflammatory cytokines | IL1B, IL1A, IL1R1 | FDPS 222/4885ADA 219/4885PDE2A 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.