Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 5/20 | 0.40 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29782912 | 0.95 | FDPS (0.41) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL21311452 | 0.94 | FDPS (0.41) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL25849033 | 0.94 | FDPS (0.41) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL25826138 | 0.82 | ADA (0.43) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL17017279 | 0.80 | ADA (0.62) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL30544611 | 0.80 | ADA (0.62) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL7155208 | 0.77 | FDPS (0.39) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL29782798 | 0.77 | ADA (0.49) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL29782906 | 0.77 | ADA (0.49) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL29782849 | 0.77 | ADA (0.67) | ADAPDE2ACYP3A4PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574217-B | Acyclic nucleoside lead compound, preparation method thereof and application thereof in pharmacy | 河南师范大学 | 2022-05-20 | — | — | CN | disclosed |