SCHEMBL25826352

SCHEMBL25826352

Bc1cc([C@]2(C#N)OC(C(B)(B)OP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)n2ncnc(N)c12

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.36
▸ P2RY2 P41231 3/20 0.31
▸ RNASEL Q05823 1/20 0.31
▸ P2RX1 P51575 1/20 0.30
▸ P2RX3 P56373 1/20 0.30
▸ P2RX2 Q9UBL9 1/20 0.30
▸ TMPRSS2 O15393 1/20 0.30
▸ P2RY1 P47900 2/20 0.30
▸ P2RY11 Q96G91 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25827054 0.91 POLRMT (0.36) POLRMTRNASELP2RX1P2RX3P2RX2
SCHEMBL25826065 0.87 POLRMT (0.44) POLRMTP2RY2P2RX1P2RX3P2RX2
SCHEMBL25826041 0.83 RNASEL (0.42) POLRMTP2RY2RNASELP2RX1P2RX3
SCHEMBL25826846 0.81 TMPRSS2 (0.32) TMPRSS2
SCHEMBL25826990 0.79 PIK3CD (0.32) TMPRSS2
SCHEMBL25827006 0.77 PIK3CD (0.31) TMPRSS2
SCHEMBL25821565 0.73 RNASEL (0.42) POLRMTP2RY2RNASELP2RX1P2RX3
SCHEMBL25821559 0.73 RNASEL (0.42) POLRMTP2RY2RNASELP2RX1P2RX3
SCHEMBL25826835 0.72 TMPRSS2 (0.47) TMPRSS2
SCHEMBL25826852 0.71 ACVRL1 (0.35) TMPRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG VIGONVITA LIFE SCIENCES CO., LTD. (CN) 2023-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG PNP, TYMP, PIGS POLRMT 139/4885P2RY2 276/4885RNASEL 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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