Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032622 | 0.94 | GAA (0.69) | GAATDP1CA1CA2MAOA | |
| SCHEMBL25827367 | 0.91 | GAA (0.58) | GAATDP1CA1CA2MAOA | |
| SCHEMBL572949 | 0.88 | TDP1 (0.56) | GAATDP1CA1CA2MAOA | |
| SCHEMBL25827510 | 0.87 | GAA (0.54) | GAATDP1CA1CA2MAOA | |
| SCHEMBL9555151 | 0.86 | GAA (0.53) | GAATDP1CA1CA2MAOA | |
| SCHEMBL22381487 | 0.84 | MAOA (0.64) | GAATDP1CA1CA2MAOA | |
| SCHEMBL2459761 | 0.84 | MAOA (0.60) | GAATDP1CA1CA2MAOA | |
| SCHEMBL25095054 | 0.83 | TDP1 (0.58) | GAATDP1CA1CA2MAOA | |
| SCHEMBL6355605 | 0.83 | GAA (0.54) | GAATDP1CA1CA2MAOA | |
| SCHEMBL3882948 | 0.83 | CAPN1 (0.63) | GAATDP1CA1CA2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061934-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-12-27 | — | — | EP | disclosed |
| US-6117842-A | INHIBITION OF BINDING OF FIBRINOGEN AND OTHER PROTEINS TO BLOOD PLATELETS, AND INHIBITING AGGREGATION OF BLOOD PLATELETS; | MERCK & CO., INC. (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1999045939-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-09-16 | — | — | WO | disclosed |