Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405019 | 0.94 | GAA (0.64) | GAATDP1MAOAMAOBCYP3A4 | |
| SCHEMBL25827510 | 0.90 | GAA (0.54) | GAATDP1MAOAMAOBCYP3A4 | |
| SCHEMBL9555151 | 0.89 | GAA (0.53) | GAATDP1MAOAMAOBCYP3A4 | |
| SCHEMBL5653695 | 0.88 | TDP1 (0.61) | GAATDP1MAOAMAOBCYP3A4 | |
| SCHEMBL29256392 | 0.88 | TDP1 (0.61) | GAATDP1MAOAMAOBCYP3A4 | |
| SCHEMBL7158127 | 0.88 | TDP1 (0.61) | GAATDP1MAOAMAOBCYP3A4 | |
| SCHEMBL25827367 | 0.88 | GAA (0.58) | GAATDP1MAOAMAOBCA1 | |
| SCHEMBL25095054 | 0.87 | TDP1 (0.58) | GAATDP1MAOAMAOBCYP3A4 | |
| SCHEMBL7207224 | 0.85 | TDP1 (0.69) | GAATDP1MAOAMAOBCYP3A4 | |
| SCHEMBL22381487 | 0.84 | MAOA (0.64) | GAATDP1MAOAMAOBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |
| CN-1046535-C | Erythromycin A 9-0-oxime derivatives endowed with antibiotic activity | ZAMBON SPA (IT) | 1999-11-17 | — | — | CN | disclosed |
| US-5847092-A | Erythromycin A 9-0 oxime derivatives endowed with antibiotic activity | ZAMBON GROUP S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |
| CN-1169727-A | Erythromycin A 9-0-oxime derivatives endowed with antibiotic activity | ZAMBON SPA (IT) | 1998-01-07 | — | — | CN | disclosed |
| EP-0797579-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018633-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1996-06-20 | — | — | WO | disclosed |