Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22743267 | 0.85 | RAB9A (0.47) | THRBAHRRAB9ANPC1RXFP1 | |
| SCHEMBL4354331 | 0.78 | ALDH1A1 (0.46) | THRBAHRLMNARAB9ANPC1 | |
| SCHEMBL6073484 | 0.72 | RAB9A (0.49) | AHRRAB9ANPC1POLBMAPT | |
| SCHEMBL5209725 | 0.72 | PIM1 (0.45) | AHRLMNARAB9ANPC1MAPT | |
| SCHEMBL3084614 | 0.72 | KDM4E (0.54) | THRBAHRRAB9ANPC1RXFP1 | |
| SCHEMBL3263497 | 0.71 | POLB (0.63) | THRBLMNARAB9ARXFP1POLB | |
| SCHEMBL7563419 | 0.71 | SMN1; SMN2 (0.49) | LMNARAB9ANPC1MAPT | |
| SCHEMBL25898537 | 0.70 | AHR (0.56) | THRBAHRLMNARAB9ANPC1 | |
| SCHEMBL23086109 | 0.68 | RXFP1 (0.54) | THRBAHRLMNANPC1RXFP1 | |
| SCHEMBL3970353 | 0.68 | THRB (0.41) | THRBAHRLMNARXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |