SCHEMBL25828115

SCHEMBL25828115

O=C(COc1ccc(C(=O)N(CCO)CCO)c2c(=O)c3ccccc3sc12)N(CCO)CCO

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.37
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
RAD52 P43351 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
RAB9A P51151 2/20 0.36
CHRM2 P08172 2/20 0.36
HTR1A P08908 2/20 0.36
ADRA2A P08913 2/20 0.36
CHRM1 P11229 2/20 0.36
TBXA2R P21731 2/20 0.36
SLC6A2 P23975 2/20 0.36
APEX1 P27695 2/20 0.36
SLC6A4 P31645 2/20 0.36
ADRA1A P35348 2/20 0.36
OPRM1 P35372 2/20 0.36
DRD3 P35462 2/20 0.36
SLC6A3 Q01959 2/20 0.36
KCNH2 Q12809 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4537591 0.86 POLB (0.38) POLBMAPTLMNARAD52CYP1A2
SCHEMBL25828113 0.81 ALDH1A1 (0.39) POLBMAPTLMNARAB9AKMT2A
SCHEMBL25556853 0.81 TSHR (0.42) POLBMAPTLMNARAD52CYP1A2
SCHEMBL25828186 0.79 RAD52 (0.37) POLBMAPTLMNARAD52CYP1A2
SCHEMBL25828107 0.77 POLB (0.43) POLBMAPTLMNARAB9AHPGD
SCHEMBL4562611 0.74 TOP2A (0.31) POLBMAPTLMNARAD52CYP1A2
SCHEMBL2385517 0.73 KDM4E (0.52) POLBMAPTLMNARAD52RAB9A
SCHEMBL6491767 0.71 PTPN1 (0.50) POLBMAPTLMNARAD52CYP1A2
SCHEMBL4538566 0.70 MAPT (0.41) POLBMAPTLMNARAD52CYP1A2
SCHEMBL31544286 0.70 GABRP (0.42) MAPTLMNACYP1A2CYP3A4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023180075-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-28 WO disclosed
EP-4249518-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-27 EP disclosed
WO-2023126223-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-06 WO disclosed
EP-4206183-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-05 EP disclosed